C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/22 (2006.01) A61K 31/436 (2006.01) A61K 31/438 (2006.01) A61P 31/18 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 223/00 (2006.01) C07D 307/00 (2006.01) C07D 311/00 (2006.01) C07D 455/02 (2006.01) C07D 491/14 (2006.01)
Patent
CA 2372197
The present invention is a novel series of functionalized heterocycles as chemokine receptor modulators of Formula (I) useful as modulators of chemokine receptor activity. The compounds are useful in the treatment and prevention of the AIDS virus. Intermediates useful in the prepartion of the final products, pharmaceutical compositions containing the final products are also taught.
L'invention concerne une nouvelle série d'hétérocycles fonctionnalisés en tant que modulateurs des récepteurs de chimiokines de formule (I) [cycle fermé] [cycle ouvert], qui conviennent comme modulateurs de l'activité des récepteurs de chimiokines. Les composés servent à traiter et à prévenir le virus du SIDA. Des intermédiaires servent dans la préparation des produits finals. L'invention traite également de compositions pharmaceutiques contenant lesdits produits finals.
Harriman Geraldine C.
Kolz Christine Nylund
Luly Jay R.
Roth Bruce David
Song Yuntao
Borden Ladner Gervais Llp
Millennium Pharmaceuticals Inc.
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