A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 9/133 (2006.01) A61K 39/002 (2006.01) A61K 39/02 (2006.01) A61K 39/12 (2006.01) A61K 39/135 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2527735
The present invention relates to vaccines directed against antigens such as membrane proteins from pathogens or tumor cells. The invention further relates to methods of forming reconstituted viral membranes, with membrane fusion activity, which are lipid bilayer membranes preferably containing natural lipids of a virus, a viral fusion protein, one or more optional further antigens as well as amphiphilic adjuvants. Pharmaceutical compositions comprising such reconstituted viral membranes are also part of the invention.
L'invention concerne des vaccins dirigés contre des antigènes tels que des protéines membranaires pathogens or tumor cells. The invention further relates to methods of forming reconstituted viral membranes, with membrane fusion activity, which are lipid bilayer membranes preferably containing natural lipids of a virus, a viral fusion protein, one or more optional further antigens as well as amphiphilic adjuvants. Pharmaceutical compositions comprising such reconstituted viral membranes are also part of the invention.
Stegmann Antonius Johannes Hendrikus
Van Berkum Johannes Henricus Gerardus
Wilschut Jan Christiaan
Bestewil Holding B.v.
Gowling Lafleur Henderson Llp
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