C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/06 (2006.01) A61K 31/4178 (2006.01) A61K 31/422 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2679849
In its many embodiments, the present invention provides a novel class of indolines as inhibitors of .alpha.2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the .alpha.2C adrenergic receptors using such compounds or pharmaceutical compositions.
L'invention concerne, dans ses nombreux modes de réalisation, une nouvelle catégorie d'indolines en tant qu'inhibiteurs des agonistes du récepteur adrénergique a2C, des procédés de préparation de ces composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés, et des procédés de traitement, de prévention, d'inhibition ou d'amélioration d'une ou plusieurs affections associées aux récepteurs adrénergiques a2C utilisant ces composés ou compositions pharmaceutiques.
Aslanian Robert G.
Boyce Christopher W.
Chao Jianhua
Fevrier Salem
Huang Chia-Yu
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Pharmacopeia Llc
Schering Corporation
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