Functionally specific antibodies

Details Functionally specific antibodies Functionally specific antibodies

A - Human Necessities

61

K

167/40

A61K 51/10 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 16/30 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340409

Diagnostic or therapeutic agents are attached to two or more antibody species having non-overlapping patterns of cross-reactivity to increase the relative amount of the active agent(s) delivered to desired target cells compared to non-target cells. The agents may be attached to monoclonal antibodies which bind to cancer cells so that a higher percentage of the active agent(s) localize on the target cells compared to each type of cross-reactive normal tissue.

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