A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61P 1/14 (2006.01) A61P 3/04 (2006.01) A61P 25/04 (2006.01)
Patent
CA 2605421
The present invention provides mammalian GPR39 gene, its coded products, and the uses in regulating appetite and sense of pain. A pharmaceutical composition and a health product comprising GPR39 protein are also provided. The health product and the pharmaceutical composition for the inhibition of appetite or sense of pain comprise safe and efficient amount of antagonists of mammalian GPR39 protein (for example 0.01-99%) and bromatologically or pharmaceutically acceptable carriers (for example 1-99.99wt%).
La présente invention se rapporte au gène GPR39 de mammifère, à ses produits de codage, et à ses utilisations dans la régulation de l~appétit et de la sensation de douleur. Une composition pharmaceutique et un produit médical comprenant la protéine GPR39 sont également fournis. Le médicament et la composition pharmaceutique destinés à inhiber l~appétit ou la sensation de douleur comprennent un taux sans danger et efficace d~antagonistes de la protéine GPR39 de mammifère (par exemple 0,01 à 99 %) et des vecteurs pharmaceutiquement ou bromatologiquement acceptables (par exemple 1 à 99,99 % en poids).
Chua Anne O.
Goodnow Robert A.
Gubler Ulrich A.
Hilton Holly
Jin Meilei
F. Hoffmann-La Roche Ag
Ridout & Maybee Llp
Shanghai Institutes For Biological Sciences Chinese Academy Of Sciences
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