Fungicidal methods and compositions for killing yeast and...

A - Human Necessities – 01 – N

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A01N 63/00 (2006.01) A61K 38/44 (2006.01) A61L 2/18 (2006.01) C12N 9/08 (2006.01) G02C 13/00 (2006.01)

Patent

CA 2167525

Methods and compositions are provided for killing or inhibiting the growth of yeast or sporular microorganisms, in the presence of a peroxide and chloride or bromide, with a haloperoxidase and at least one antimicrobial activity enhancing agent. Suitable antimicrobial activity enhancing agents include certain alpha-amino acids, and are preferably compounds of formula (I) wherein R1 is hydrogen, and unsubstituted, or hydroxy or amino substituted straight or branched chain aklyl group having 1 to 6 carbon atoms, or an unsubstituted, or hydroxy or amino substituted arylalkyl group having from 7 to 12 carbon atoms, and R2 is hydrogen or straight or branched chain alkyl group having from 1 to 6 carbon atoms.

Procédés et compositions utilisés pour réduire à néant ou inhiber la croissance de micro-organismes de levure ou des micro-organismes sporulaires, en présence d'un peroxyde et de chlorure ou de bromure, avec une haloperoxydase et au moins un agent renforçant l'acitivité antimicrobienne. Les agents appropriés renforçant l'activité antimicrobienne peuvent être certains acides alpha -aminés et sont, de préférence, des composés de formule (I) où R1 représente hydrogène, un groupe alkyle à chaîne linéaire ou ramifiée non substitué ou à substitution hydroxy ou amino contenant de 1 à 6 atomes de carbone ou un groupe arylalkyl non substitué à substitution hydroxy ou amino contenant de 7 à 12 atomes de carbone et R2 représente hydrogène ou un groupe alkyle à chaîne linéaire ou ramifiée contenant de 1 à 6 atomes de carbone.

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