Furo- and thieno[3,2-c] pyridines

Details Furo- and thieno[3,2-c] pyridines Furo- and thieno[3,2-c] pyridines

C - Chemistry, Metallurgy

07

D

C07D 491/048 (2006.01) A61K 31/4355 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2711078

Furo[3,2-c]Pyridine and Thieno[3,2-c] pyridine compounds of Formula (I), and pharmaceutically acceptable salts thereof, preparation, intermediates, pharmaceutical compositions, and use, such as in disease treatment, including cancers, including conditions in which EMT is involved, including conditions mediated by protein kinase activity such as RON and/or MET.

L'invention concerne des composés de furo[3,2-c]pyridine et de thiéno[3,2-c]pyridine de formule (I), et leurs sels pharmaceutiquement acceptables, une préparation, des produits intermédiaires, des compositions pharmaceutiques, et une utilisation, telle que le traitement de maladies, y compris des cancers, y compris des affections dans lesquels EMT est impliqué, y compris des états provoqués par une activité de protéine kinase telle que RON et/ou MET.

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