C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/048 (2006.01) A61K 31/435 (2006.01) A61K 31/4355 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2227695
Novel heterocyclic ether compounds having the formula (I) wherein A, m, R, X, Y1, Y2 and Y3 are specifically defined, which are useful in selectively controlling chemical synaptic transmission; therapeutically-effective pharmaceutical compositions thereof; and use of said compositions to selectively control synaptic transmission in mammals.
Nouveaux composés d'éther hétérocyclique de formule (I) où A, m, R, X, Y<1>, Y<2> et Y<3> sont définis spécifiquement. Ces composés sont utiles pour gérer sélectivement la transmission synaptique par voie chimique. L'invention porte aussi sur des compositions pharmaceutiques de ces composés, efficaces sur le plan thérapeutique, ainsi que sur l'usage de ces compositions pour gérer sélectivement la transmission synaptique chez les mammifères.
Daanen Jerome F.
Dart Michael J.
Elliott Richard L.
Holladay Mark W.
Ryther Keith B.
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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