Furopyridine, thienopyridine, pyrrolopyridine and related...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/048 (2006.01) A61K 31/4355 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2285263

Novel heterocyclic ether compounds having formula (I) wherein A, m, R, X, Y1, Y2 and Y3 are specifically defined, which are useful in selectively controlling chemical synaptic transmission; therapeutically- effective pharmaceutical compositions thereof; and use of said compositions to selectively control synaptic transmission in mammals.

La présente invention concerne un composé éther hétérocyclique représenté par la formule générale (I) et convenant particulièrement au contrôle sélectif de la chimio-transmission synaptique. Dans cette formule, A, m, R, X, Y<1>, Y<2> et Y<3> sont conformes à la description qui en est donnée par les revendications. L'invention concerne également des compositions pharmaceutiques à base de ces produits, lesquelles compositions présentent une efficacité thérapeutique. L'invention concerne enfin l'utilisation de ces compositions pour le contrôle sélectif de la transmission synaptique chez les mammifères.

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