Further improvements relating to the radiolabelling of proteins

C - Chemistry – Metallurgy – 12 – P

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C12P 21/02 (2006.01) A61K 47/48 (2006.01) A61K 51/08 (2006.01) C07K 1/107 (2006.01) C07K 2/00 (2006.01) C07K 16/30 (2006.01) C07K 17/02 (2006.01) C12P 21/08 (2006.01) A61K 43/00 (1990.01)

Patent

CA 2125975

2125975 9311796 PCTABS00022 A structurally modified protein is provided that will bind to a tumour-associated structure wherein the amino group in at least one basic amino acid in the binding protein is structurally modified to convert the amino group, -NH2, to the grouping -NH-CO-X-NHR in which R is H or an amino protecting group and the grouping -CO-X-NHR is the residue of a peptide of the formula NHR-X-COOH capable of acting as a substrate for a phosphokinase.

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