Fused 1,2,5-oxadiazole-2-oxides

Details Fused 1,2,5-oxadiazole-2-oxides Fused 1,2,5-oxadiazole-2-oxides

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/42 (2006.01) A61K 31/435 (2006.01) A61K 31/55 (2006.01) C07D 271/12 (2006.01)

Patent

CA 2098058

23233-279 ABSTRACT The invention relates to fused 1,2,5-oxadiazole-2- oxides of the general formula I Image I in which A denotes Image , -(CH2)n-Y- , -CH2-Z-CO-, Image or Image , wherein R1 is for example, COOH, R2 and R3 are, for example, a (C1-C6)-alkyl, and X, Y and Z are, for example, -S-. The compounds of the formula I have useful pharmacological properties and can be used for the control and prevention of disorders of the cardiovascular system, in particular for the control and prevention of angina pectoris and for the treatment of erectile dysfunctions.

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