Fused aromatic difluoromethanephosphonates as protein...

Details Fused aromatic difluoromethanephosphonates as protein... Fused aromatic difluoromethanephosphonates as protein...

C - Chemistry, Metallurgy

07

F

C07F 9/60 (2006.01) A61K 31/662 (2006.01) A61K 31/675 (2006.01) A61P 3/10 (2006.01) A61P 35/00 (2006.01) C07F 9/38 (2006.01) C07F 9/40 (2006.01)

Patent

CA 2675142

The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated diseases, including diabetes.

La présente invention concerne une nouvelle classe de composés représentés par la formule ci-dessous, qui sont des inhibiteurs de l'enzyme PTP-1B. Cette invention concerne aussi des compositions pharmaceutiques qui comprennent les composés représentés par la formule I ci-dessous et des procédés de traitement et de prévention des maladies induites par la PTP-1B, notamment le diabète.

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