Fused benzeneoxyacetic acid derivatives

Details Fused benzeneoxyacetic acid derivatives Fused benzeneoxyacetic acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 231/12 (2006.01) A61K 31/395 (2006.01) C07D 233/54 (2006.01) C07D 233/70 (2006.01) C07D 233/84 (2006.01) C07D 235/26 (2006.01) C07D 249/04 (2006.01) C07D 261/08 (2006.01) C07D 263/32 (2006.01) C07D 271/06 (2006.01) C07D 275/02 (2006.01) C07D 277/30 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2085844

Abstract A fused benzeneoxyacetic acid derivative of the formula (I): Image (I) wherein Image is (i) Image , (ii) Image , (iii) Image or (iv) Image ; R1 is OH, alkoxy, (alkyl)amino, residue of an amino acid; A is phenyl, alkyl substituted by phenyl, residue of an imidazole, imidazole-2- yloxy(thio), 2-oxoimidazole, pyrazole, oxadiazole, oxazole, triazole, isoxazole or isothiazole, in the group of benzene may be substituted by one to three of alkyl, alkoxy, halogen, nitro or trihalomethyl; e is 3-5; 145 f is 1-3; p is 1-4; q is 0-2; r is 1-4; s is 0-3) and salts thereof possess an agonistic on PGI2 receptor, so it is useful for prevention and/or treatment of thrombosis, arteriosclerosis, inchemic heart diseases, gastric alcer and hypertention. 146

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