Fused bicyclic or tricyclic amino acids

Details Fused bicyclic or tricyclic amino acids Fused bicyclic or tricyclic amino acids

C - Chemistry, Metallurgy

07

C

C07C 229/28 (2006.01) A61K 31/195 (2006.01) A61P 25/02 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) C07C 61/12 (2006.01)

Patent

CA 2444053

The compounds of the instant invention are bicyclic or tricyclic amino acids useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis, neuropathological disorders, sleep disorders, visceral pain disorders, and gastrointestinal disorders. Processes for the preparation of the final products and intermediates useful in the process are included. Pharmaceutical compositions containing one or more of the compounds are also included.

Les composés selon la présente invention sont des acides aminés bicycliques ou tricycliques utiles dans le traitement de l'épilepsie, de pertes de connaissance, de l'hypocinésie, de troubles crâniens, de troubles neurodégéneratifs, de la dépression, de l'anxiété, de la panique, de la douleur, de l'arthrite, de troubles neuropathologiques, de troubles du sommeil, de troubles de la douleur viscérale, et de troubles gastro-intestinaux. L'invention concerne des procédés de préparation des produits finaux et des intermédiaires utiles dans le procédé. L'invention concerne également des compositions pharmaceutiques contenant un ou plusieurs desdits composés.

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