Fused bicyclic pyrimidine compounds as aurora kinase inhibitors

Details Fused bicyclic pyrimidine compounds as aurora kinase inhibitors Fused bicyclic pyrimidine compounds as aurora kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 491/048 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2722220

Fused bicyclic pyrimidine compounds of formula (I) defined herein. Also disclosed are a method for inhibiting Au-rora kinase activity and a method for treating cancer with these compounds.

Composés de pyrimidine bicycliques fusionnés représentés par la formule (I) définie dans le descriptif. L'invention concerne également un procédé servant à inhiber l'activité d'Aurora kinase et un procédé de traitement du cancer au moyen de ces composés.

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