Fused cyclic compounds and medicinal use thereof

A - Human Necessities – 61 – K

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A61K 31/4184 (2006.01) A61K 31/42 (2006.01) A61K 31/427 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) A61K 31/4523 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61K 31/519 (2006.01) A61K 31/52 (2006.01) A61K 31/53 (2006.01) A61K 31/55 (2006.01) A61K 31/7076 (2006.01) A61K 38/21 (2006.01) A61K 45/06 (2006.01) A61P 1/16 (2006.01) A61P 31/12 (2006.01) A61P 43/00 (2006.01) C07D 209/12 (2006.01) C07D 235/18 (2006.01) C07D 235/30 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 401/12

Patent

CA 2423800

Fused cyclic compounds represented by the following general formula [I] or pharmaceutically acceptable salts thereof and remedies for hepatitis C containing these compounds: [I] wherein each symbol is as defined in the description. Because of having an effect against hepatitis C virus (HVC) based on an HCV polymerase inhibitory effect, these compounds are useful as remedies or preventives for hepatitis C.

L'invention concerne des composés cycliques condensés représentés par la formule générale (I) suivante, ou des sels pharmaceutiquement acceptables de ceux-ci et des agents permettant le traitement de l'hépatite C contenant ces composés : (I) . Chaque symbole a la signification indiquée dans le descriptif. Grâce à leur action anti-virus de l'hépatite C (VHC) résultant de leur effet inhibiteur sur la polymérase du VHC, ces composés sont utiles en tant qu'agents thérapeutiques ou préventifs pour le traitement de l'hépatite C.

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