Fused derivatives of pyrazole

Details Fused derivatives of pyrazole Fused derivatives of pyrazole

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2557575

Compounds of the formula (Ia), (Ib) or (Ic), wherein A, B, X, Y, Z, W, k, R1, R2, R3, R4 and R5 are those defined herein, and compositions comprising the same. The present invention also provides methods for preparing said compounds and using the same in treating p38 mediated disorders in a subject.

L'invention concerne des composés représentés par la formule Ia, Ib ou Ic dans laquelle A, B, X, Y, Z, W, k, R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ sont tels que définis dans la description, et des compositions comprenant lesdits composés. L'invention concerne également des procédés permettant de préparer ces composés et leur utilisation pour traiter des troubles induits chez un sujet par p38.

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