C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/12 (2006.01) A61K 31/519 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) C07D 487/14 (2006.01)
Patent
CA 2738650
The invention encompasses novel compounds and pharmaceutically acceptable salts thereof and compositions including therapeutically or prophylactically effective amounts of such compounds or pharmaceutically acceptable salts thereof. The invention also encompasses methods for treating or preventing diseases and disorders associated abnormal cell growth, for example, treating or preventing cancer or tumor growth, which methods include administering to a mammal in need thereof a composi-tion comprising a therapeutically or prophylactically effective amount of a compound of the invention or a pharmaceutically acceptable salt thereof.
La présente invention concerne de nouveaux composés et leurs sels pharmaceutiquement acceptables et des compositions comprenant des quantités thérapeutiquement ou prophylactiquement efficaces de tels composés ou de tels sels pharmaceutiquement acceptables de ceux-ci. Linvention concerne également des méthodes de traitement ou de prévention de maladies et de troubles associés à une croissance cellulaire anormale, par exemple, de traitement ou de prévention de la croissance de tumeurs ou du cancer, lesquelles méthodes comprennent ladministration à un mammifère qui en a besoin d'une composition comprenant une quantité thérapeutiquement ou prophylactiquement efficace dun composé de linvention ou dun de ses sels pharmaceutiquement acceptables.
Hosmane Ramachandra S.
Kumar Raj
Raman Venu
Johns Hopkins University
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
University Of Maryland Baltimore County
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