C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/42 (2006.01) A61K 31/4355 (2006.01) A61K 31/4365 (2006.01) A61K 31/437 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 239/94 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 413/04 (2006.01) C07D 417/12 (2006.01) C07D
Patent
CA 2407593
Medicinal compositions which are useful as phosphatidylinositol 3-kinase (PI3K) inhibitors and anticancer agents; and novel bicyclic or tricyclic condensed heteroaryl derivatives or salts thereof having favorable effects of inhibiting PI3K and suppressing the proliferation of cancer cells.
L'invention concerne des compositions médicinales s'utilisant comme inhibiteurs de phosphatidylinositol 3-kinase (PI3K) et comme agents anticancéreux. L'invention concerne également de nouveaux dérivés d'hétéroaryle condensés bicycliques ou tricycliques ou leurs sels produisant des effets bénéfiques sur l'inhibition de la PI3K et sur la prolifération de cellules cancéreuses.
Hayakawa Masahiko
Kaizawa Hiroyuki
Kawaguchi Ken-Ichi
Koizumi Tomonobu
Matsuda Koyo
Astellas Pharma Inc.
Dennison Associates
Imperial Cancer Research Technology Ltd.
Ludwig Institute For Cancer Research
Yamanouchi Pharmaceutical Co. Ltd.
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