Fused heterobicyclo substituted phenyl metabotropic...

C - Chemistry – Metallurgy – 07 – D

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C07D 513/04 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) C07D 401/10 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2498237

Phenyl compounds substituted with a fused-heterobicyclo moiety, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.

L'invention concerne des composés phényle substitués par un fragment hétérobicyclo fusionné, qui sont des modulateurs du mGluR5 utiles dans le traitement de troubles psychiatriques et de troubles de l'humeur de type schizophrénie, anxiété, dépression, et panique, ainsi que dans le traitement de la douleur et d'autres maladies.

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