Fused heterocyclic compounds, and compositions and uses thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/04 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2606760

Fused heterocyclic compounds are disclosed that have formula (1): where A, B, L, N, R1, R3, R4', Y and Z are as defined herein. The compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

L'invention concerne des composés hétérocycliques fusionnés de formule (I), dans laquelle A, B, L, N, R1, R3, R4', Y et Z sont tels que définis dans la description. Les composés et leurs compositions pharmaceutiques sont utilisés pour la prévention et le traitement d'une grande variété d'états chez des mammifères, y compris les êtres humains, à savoir entre autres, les douleurs, les inflammations, les troubles cognitifs, l'anxiété, la dépression et autres.

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