Fused heterocyclic compounds and their use as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 403/04 (2006.01) A61K 31/423 (2006.01) A61K 31/538 (2006.01) A61K 31/542 (2006.01) A61P 9/04 (2006.01) A61P 9/12 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2635541

The present invention relates to wherein each symbol is as defined in the specification. The compound has a superior mineral corticoidreceptorantagonistic action and is useful as an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like, a compound having a fused heterocycle, or a prodrug thereof, or a salt thereof; and an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like.

La présente invention concerne un composé de formule (Ia), dans laquelle chaque symbole est tel que défini dans la description. Ce composé présente une action antagoniste vis-à-vis des récepteurs des corticoïdes et est utile comme agent pour la prévention ou le traitement de l'hypertension, de l'insuffisance cardiaque et analogue. L'invention concerne également un composé comprenant un hétérocycle fusionné, ou un promédicament ou un sel de celui-ci, ainsi qu'un agent pour la prévention ou le traitement de l'hypertension, de l'insuffisance cardiaque et analogue.

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