C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/00 (2006.01)
Patent
CA 2556320
The present invention is directed to compounds of formula: (I); wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, R1, R2, R3, R4, and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds for treating gastrointestinal disorders.
La présente invention se rapporte à des composés de la formule (I): dans laquelle X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, R1, R2, R3, R4, et n sont tels que définis pour la formule I dans la description. L'invention concerne également des procédés de préparation de ces composés, de nouveaux intermédiaires utilisés pour la préparation desdits composés, des compositions pharmaceutiques les contenant et leur utilisation en thérapie.
Edwards Louise
Isaac Methvin
Johansson Martin
Kers Annika
Mcleod Donald
Astrazeneca Ab
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Nps Pharmaceuticals Inc.
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