Fused heterocyclic compounds useful as inhibitors of histone...

Details Fused heterocyclic compounds useful as inhibitors of histone... Fused heterocyclic compounds useful as inhibitors of histone...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4353 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2596015

Disclosed are compounds of formula (I) that inhibit histone deacetylase (HDAC) enzymatic activity, pharmaceutical compositions comprising such compounds, as well as methods to treat conditions, particularly proliferative conditions, mediated at least in part by HDAC, wherein A, W, W1, W2, Ar2, and G are described herein.

L'invention concerne des composés de formule (I) inhibant l'activité enzymatique de l'histone déacétylase (HDAC), des compositions pharmaceutiques renfermant ceux-ci, ainsi que des méthodes de traitement d'états, notamment des états prolifératifs, induits au moins partiellement par HDAC, A, W, W1, W2, Ar2 et G étant décrits dans la description.

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