Fused heterocyclic derivatives and methods of use as c-met...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/4355 (2006.01) A61K 31/4365 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01) C07D 493/04 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2711101

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Certains composés sont efficaces pour la prophylaxie et le traitement de maladies telles que les maladies médiées par HGF. L'invention englobe de nouveaux composés, des analogues, des promédicaments et des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement de maladies ou de troubles qui mettent en cause le cancer et similaires. La présente invention concerne également des procédés de fabrication de tels composés ainsi que des intermédiaires utiles dans de tels procédés.

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