Fused imidazole and triazole derivatives as 5-htl receptor...

Details Fused imidazole and triazole derivatives as 5-htl receptor... Fused imidazole and triazole derivatives as 5-htl receptor...

C - Chemistry, Metallurgy

07

D

C07D 473/00 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/52 (2006.01) C07D 403/02 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2134986

2134986 9323396 PCTABS00028 Compounds of formula (I) wherein Q represents the residue of a six-membered aromatic or heteroaromatic nucleus containing zero, one or two nitrogen atoms; V represents nitrogen or C-A2; E represents a bond or a straight or branched alkylene chain containing from 1 to 4 carbon atoms; F represents a group of formula (a); U represents nitrogen or C-R2; B represents oxygen, sulphur or N-R3; R1 represents -CH2.CHR4.NR6R7 or a group of formula (i), (ii), (iii) or (iv); are selective agonists of 5-HT1-like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a selective agonist of these receptors is indicated.

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