Fused imidazole carboxamides as trpv3 modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 513/04 (2006.01) A61K 31/429 (2006.01) A61K 31/437 (2006.01) A61P 29/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2746077

The present invention provides transient receptor potential vanilloid (TRPV) modulators of formula (I). In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPV3. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRP V3.

L'invention concerne des modulateurs de récepteurs vanilloïdes à potentiel de récepteur transitoire (TRPV) de formule (I). L'invention concerne en particulier des composés utiles dans le traitement ou la prévention de maladies, d'états et/ou de troubles induits par le TRPV3. L'invention concerne également des procédés de préparation de ces composés, d'intermédiaires utilisés dans leur synthèse, de compositions pharmaceutiques les contenant, ainsi que des méthodes de traitement ou de prévention de maladies, d'états et/ou de troubles induits par le TRPV3.

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