Fused imidazole derivatives as trpv3 antagonist

Details Fused imidazole derivatives as trpv3 antagonist Fused imidazole derivatives as trpv3 antagonist

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) C07D 235/02 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2744911

The present invention provides transient receptor potential vanilloid (TRPV) modulators of formula (I). In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPV3. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRP V3.

La présente invention concerne des modulateurs de récepteur vanilloïde à potentiel de récepteur transitoire (TRVP) de formule (I). En particulier, les composés décrits dans l'invention sont utiles pour traiter ou prévenir des maladies, des états et/ou des affections modulés par TRPV3. L'invention concerne également des procédés de préparation des composés décrits ici, des intermédiaires utilisés dans leur synthèse, des compositions pharmaceutiques les contenant et des procédés de traitement ou de prévention de maladies, d'états et/ou d'affections modulés par TRPV3. (Formule I) (I)

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