Fused pyridine derivatives for use as vanilloid receptor...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2441599

The invention provides compounds of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in the description, and the preparation thereof. The compounds of formula I are functional blockers of the human vanilloid receptor 1 (hVR1) and are useful as pharmaceuticals; in particular for treating pain.

L'invention porte sur des composés de formule (I) dans laquelle: R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ sont définis dans la description, et sur leur préparation. Lesdits composés peuvent être utilisés comme produits pharmaceutiques.

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