C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2441599
The invention provides compounds of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in the description, and the preparation thereof. The compounds of formula I are functional blockers of the human vanilloid receptor 1 (hVR1) and are useful as pharmaceuticals; in particular for treating pain.
L'invention porte sur des composés de formule (I) dans laquelle: R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ sont définis dans la description, et sur leur préparation. Lesdits composés peuvent être utilisés comme produits pharmaceutiques.
Culshaw Andrew James
Gull Peter
Hallett Allan
Kim Hong-Yong
Liu Yugang
Fetherstonhaugh & Co.
Novartis Ag
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