C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01) C07D 498/10 (2006.01) C07D 513/14 (2006.01)
Patent
CA 2709202
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4--mediated disorders, such as cancer. The subject compounds are fused pyridine, pyrimide and triazine derivatives.
La présente invention concerne des composés, des compositions pharmaceutiques et des méthodes utiles dans le traitement de troubles médiés par la CDK4, tels que le cancer. Les composés de l'invention sont des dérivés condensés de la pyridine, de la pyrimidine et de la triazine.
Connors Richard V.
Dai Kang
Deignan Jeffrey
Eksterowicz John
Fan Pingchen
Amgen Inc.
Gowling Lafleur Henderson Llp
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