Fused pyridines active as inhibitors of c-met

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/4709 (2006.01) A61P 9/00 (2006.01) A61P 27/02 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2712791

Fused pyridines of formula (I) and the pharmaceutically acceptable salts thereof have activity as inhibitors of c-Met and may thus be used to treat various diseases and disorders including cancer. Processes for synthesizing the compounds are also described.

Les pyridines condensées de formule (I) selon l'invention et leurs sels pharmaceutiquement acceptables ont une activité d'inhibiteurs de c-MET et peuvent, par conséquent, être utilisés pour traiter divers troubles et maladies comprenant le cancer. Des procédés de synthèse desdits composés sont également décrits.

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