Fused pyrimidine derivative, process for preparation of same...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 487/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2067221

It is disclosed herein that a fused pyrimidine derivative represented by the general formula [I] Image [I] wherein R1, R2, R3, Y, Z and m are as defined in the specification; and a pharmaceutically acceptable acid addition salt thereof, as well as a process for producing same and a pharmaceutical preparation comprising the same as an active ingredient. In particular, the pharmaceutical preparation of the present is useful for a treatment of hypoxemia associated with respiratory diseases.

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