Fused pyrimidine derivatives as trpv3 modulators

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01)

Patent

CA 2724008

The present invention related to fused pyrimidine derivatives, which are useful as Transient Receptor Potential Vanilloid 3 (TRPV3) receptors, methods of treating deseases, disorders, conditions modulated by TRPV3. The present invention having the formula (I) and its pharmaceutically acceptable salts thereof, and its processes thereof, wherein all variables are as described herein.

La présente invention concerne des dérivés de pyrimidine condensée, qui sont utiles en tant que récepteurs de vanilloïde 3 à potentiel de récepteur transitoire (TRPV3), des procédés de traitement de maladies, troubles, pathologies modulés par TRPV3. La présente invention concerne la formule (I) et ses sels pharmaceutiquement acceptables, et ses procédés, où toutes les variables sont comme présentement décrit.

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