Fused pyrimidines as antagonists of the corticotropin...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/70 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 51/04 (2006.01) A61P 25/00 (2006.01) C07D 239/94 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2446514

The present invention provides compounds of formula (I) including stereoisomers, prodrugs and pharmaceutically acceptable salts or solvates thereof wherein the variables are as defined in the description, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions mediated by corticotropin-releasing factor (CRF).

L'invention porte sur des composés représentés par la formule (I) comprenant des stéréoisomères, des promédicaments, et des sels ou des solvants de ces derniers pharmaceutiquement acceptables, les variables étant telles que définies dans la description, sur des procédés de préparation correspondants, sur des compositions pharmaceutiques les contenant et sur leur utilisation dans le traitement de pathologies médiées par la corticolibérine (CRF).

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