Fused quinazolinones and preparation thereof

C - Chemistry – Metallurgy – 07 – D

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260/242.01

C07D 487/04 (2006.01) C07D 239/84 (2006.01)

Patent

CA 1089853

FUSED QUINAZOLINONES AND PREPARATION THEREOF ABSTRACT OF THE DISCLOSURE Tricyclic quinazolines of the formula, Image wherein R1, R2, R3, R4 and A are as defined in the specification, such as 4,5-dihydro-5-arylimidazo- [1,2-a]quinazolines, 4,5-dihydro-5-aryl-s-triazolo- [4,3-a]qulnazolines and 4,5-dihydro-5-aryltetrazolo- [1,5-a]quinazolines having anti-inflammatory and analgesic activity are, for example, prepared by reducing the corresponding 4,5-unsaturated compounds, and then, if necessary, by alkylating the thus produced compounds.

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