Fused quinoxaline derivatives as inhibitors of akt activity

Details Fused quinoxaline derivatives as inhibitors of akt activity Fused quinoxaline derivatives as inhibitors of akt activity

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/498 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 519/00 (2006.01) C07D 519/04 (2006.01)

Patent

CA 2481241

The present invention is directed to compounds comprising a ring-fused quinoxalinyl moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.

Cette invention a trait une fraction de quinoxalinyl à anneaux fusionnés inhibant l'activité d'Akt, une serine/thréonine protéine kinase. Elle concerne également des compositions pour chimiothérapie contenant ces composés ainsi que des méthodes de traitement du cancer consistant à administrer lesdits composés.

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