Fused ring phenylpyrazole compounds

Details Fused ring phenylpyrazole compounds Fused ring phenylpyrazole compounds

C - Chemistry, Metallurgy

07

D

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C07D 491/20 (2006.01) C07C 49/743 (2006.01) C07D 231/54 (2006.01)

Patent

CA 1167040

D.N. 4671A FUSED RING PHENYLPYRAZOLE COMPOUNDS ABSTRACT Compounds of the formula Image where R is hydrogen, methyl, ethyl, propyl, 2-propenyl or 2-propynyl and R' is hydrogen or fluoro possess glucocorticoid activity. The compounds where R is H are prepared by reacting a compound of the formula Image with (1H,3H)-pyrimidine-2,4,5,6-tetrone. The compounds where R is other than hydrogen are prepared by reacting a compound where R is hydrogen with the appropriate alkylating agent.

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