Fused soluble mhc heterodimer-peptide complexes and their uses

Details Fused soluble mhc heterodimer-peptide complexes and their uses Fused soluble mhc heterodimer-peptide complexes and their uses

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 39/385 (2006.01) C07K 14/47 (2006.01) C07K 14/74 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C07K 19/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 9/88 (2006.01) C12N 9/96 (2006.01) C12N 15/12 (2006.01) C12N 15/60 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2224205

Immune modulators, such as soluble, fused MHC heterodimers and soluble, fused MHC heterodimer:peptide complexes, are described. Related methods and peptides are also disclosed. In a preferred aspect, these mediators and methods are related to autoimmunity.

L'invention porte sur des immunomodulateurs tels que des complexes solubles d'hétérodimères fusionnés de CMH et de peptides, et sur des procédés et peptides associés. Dans l'une des variantes préférées, ces médiateurs et procédés ont trait à l'autoimmunité.

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