Fused tri-heterocyclic compounds

Details Fused tri-heterocyclic compounds Fused tri-heterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 487/14 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2389634

Fused tri-heterocyclic compounds of formula: (see formula I) R1 is H or alkyl; R2 is H, alkyl, alkenyl, aryl, heteroaryl, cyclyl, or heterocyclyl; R3 and R4, independently, is H, alkyl, alkenyl, aryl, heteroaryl, cyclyl, heterocyclyl, or (CR a R b)m X(CR c R d)n Y; in which X is a bond, O, S, or NR e; Y is alkoxy, aryloxy, heteroaryloxy, OC(O)R e, C(O)R e, N(R e R e'), NR e C(O)R e', S(O)2R e, or SR e; each of m and n, independently, is 1, 2, 3, 4, or 5; each of R a, R b, R c, R d, R e, and R e', independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl; and R5 is H or halogen.

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