Fused tricyclic heteroaromatic derivatives

Details Fused tricyclic heteroaromatic derivatives Fused tricyclic heteroaromatic derivatives

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 231/54 (2006.01) C07D 239/70 (2006.01) C07D 261/20 (2006.01) C07D 413/04 (2006.01) C07D 471/04 (2006.01) C07D 491/052 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2168739

A class of fused tricyclic heteroaromatic compounds of formula (I), or a salt thereof or a prodrug thereof, containing a fused pyrazole. oxazole or pyrimidine ring are ligands for dopamine receptor subtypes within the body and are therefore of use in the treatment and/or prevention of disorders of the dopamine system, such as schizophrenia.

L'invention se rapporte à une classe de composés hétéroaromatiques tricycliques de formule (I) ou à un de leurs sels ou de leurs promédicaments; ces composés comprenant un cycle pyrazole, oxazole ou pyrimidine fusionné sont des ligands pour les sous-types de récepteurs dopaminergiques dans le corps et s'avèrent donc utiles pour le traitement des troubles du système dopaminergique, et en particulier pour le traitement de la schizophrénie.

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