Fused tricyclic heteroaromatic derivatives as dopamine...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/06 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 231/54 (2006.01) C07D 231/56 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 491/04 (2006.01) C07D 491/052 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2168738

A class of fused tricyclic heteroaro- matic compounds of formula (I), or a salt thereof or a prodrug thereof containing a fused pyrazole ring are ligands for dopamine receptor subtypes within the body and are therefore of use in the treatment and/or pre- vention of disorders of the dopamine sys- tem, such as schizophrenia.

Une classe de composés hétéroaromatiques tricycliques fusionnés de formule (I) ou un de leurs sel ou promédicaments, contenant un cycle pyrazole fusionné, sont des ligands de sous-types de récepteur de la dopamine dans le corps, et s'avèrent donc utiles dans le traitement et/ou la prévention des troubles du système dopaminergique, comme la schizophrénie.

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