Fusion partner and its product

C - Chemistry – Metallurgy – 12 – P

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167/39, 195/1.10

C12P 21/02 (2006.01) A61K 39/395 (2006.01) C07K 16/08 (2006.01) C07K 16/34 (2006.01) C12N 5/02 (2006.01)

Patent

CA 1240628

-40- Abstract By careful screening and mutation, a human- murine hybridoma suitable as a fusion partner for immor- talizing an antibody-secreting as a cell has been generated. The trioma fusion products of this immortalizing partner are stable producers of human monoclonal antibodies. A trioma which produces monoclonal human anti-varicella zoter is disclosed. A human anti-A IgM is also produced using this general method by the trioma S-H22 and by an alternate hybrid, HHA1.

471399

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