C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01)
Patent
CA 2653438
The present invention provides a fusion peptide comprising at least a component (I), wherein component (I) comprises a transporter peptide, and a component (II), selected from a peptide inhibiting interaction of neuronal N-methyl-D-aspartate receptor (NMDAR) with NMDAR interacting proteins, wherein component (II) entirely consists of D-enantiomeric amino acids. The present invention furthermore provides an inventive pharmaceutical composition, comprising the inventive fusion peptide and methods for administering the same as well as kits and uses employing the inventive fusion peptide.
La présente invention concerne un peptide de fusion qui comprend au moins un composant (I), ledit composant (I) comprenant un peptide transporteur, et un composant (II) choisi parmi les peptides qui inhibent l'interaction entre le récepteur neuronal du N-méthyl-D-aspartate (NMDAR) et les protéines qui interagissent avec le NMDAR, ledit composant (II) consistant entièrement en acides aminés D-énantiomères. La présente invention concerne en outre une composition pharmaceutique innovante qui comprend le peptide de fusion de l'invention, ainsi que des procédés d'administration de celle-ci, de même que des kits et des utilisations employant le peptide de fusion de l'invention.
Kirby Eades Gale Baker
Xigen S.a.
LandOfFree
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