Fusion polypeptides

Details Fusion polypeptides Fusion polypeptides

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/16 (2006.01) C07K 1/22 (2006.01) C07K 14/485 (2006.01) C07K 14/575 (2006.01) C07K 14/60 (2006.01) C07K 14/605 (2006.01) C07K 14/655 (2006.01) C07K 14/665 (2006.01) C12N 9/22 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2094512

2094512 9210576 PCTABS00013 A non-naturally-occurring fusion protein comprising an extension peptide portion covalently linked at its C-terminus to the N-terminus of a biologically active portion is disclosed. The extension peptide portion can be removed by DPP IV cleavage. A use of fusion proteins with DPP IV cleavable extension peptide portions in medecinal preparations is disclosed. A method of purifying desired proteins from a mixture containing a fusion protein is disclosed.

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