Fusion polypeptides capable of activating receptors

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 16/28 (2006.01) C07K 14/515 (2006.01)

Patent

CA 2550551

A fusion polypeptide comprising (A)x-M-(A~)Y, wherein A and A~ are each polypeptides capable of binding a target receptor. The fusion polypeptides of the invention form multimeric proteins which activate the target receptor. A and A~ may be each be an antibody or fragment derived form an antibody specific for a target receptor. The antibody or fragment may be the same or different ScFv fragments, and/or a ligand or ligand fragment, or derivative, capable of binding the target protein. M is a multimerizing component, and X and Y are independently a number between 1-10.

L'invention concerne un polypeptide hybride représenté par la formule générale (A)¿x?-M-(A')¿y?, dans laquelle A et A' désignent chacun des polypeptides capables de fixer un récepteur cible. Les polypeptides hybrides de l'invention forment des protéines multimériques qui activent le récepteur cible. A et A' peuvent désigner, chacun, un anticorps ou un fragment dérivé d'un anticorps spécifique pour un récepteur cible, tels que des fragments ScFv identiques ou différents, et/ou un ligand ou un fragment de ligand ou un dérivé capable de fixer la protéine cible, M désigne un composant de multimérisation et X et Y désignent chacun un nombre compris entre 1 et 10.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Fusion polypeptides capable of activating receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fusion polypeptides capable of activating receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fusion polypeptides capable of activating receptors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1780793

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.