C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/435 (2006.01) C07K 14/515 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2486649
The present application describes fusion proteins that includes coiled coil domain capable of forming dimers or multimers, in particular that coiled coil domain from GCN4, cartilage matrix protein, cartilage oligomeric matrix protein or matrilin, fused to a further domain, in particular those derived from angiopoietin, an ephrin, thrombospondin, VEGF, EGF, PDGF, FGF, NGF, erythropoietin, an interleukin or RANKL.
L'invention concerne des protéines de fusion qui contiennent un domaine superhélice capable de former des dimères ou des multimères, notamment le domaine superhélice de GCN4, la protéine matricielle du cartilage, la protéine matricielle oligomère du cartilage ou matriline, fusionnée à d'autres domaines, notamment les domaines dérivés de l'angiopoïétine, d'une éphrine, de la thrombospondine, de VEGF, de EGF, de PDGF, de FGF, de NGF, de l'érythropoïétine, d'une interleukine ou de RANKL.
Aprogen Inc.
Koh Gou Young
Sim & Mcburney
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