Fusion proteins and particles

Details Fusion proteins and particles Fusion proteins and particles

C - Chemistry, Metallurgy

12

N

167/129, 530/13,

C12N 15/62 (2006.01) A61K 39/00 (2006.01) C07K 14/11 (2006.01) C07K 14/16 (2006.01) C07K 14/555 (2006.01) C07K 17/00 (2006.01) C07K 19/00 (2006.01) G01N 33/543 (2006.01)

Patent

CA 1339263

Fusion proteins comprise a first amino acid sequence and a second amino acid sequence. The first amino acid sequence is derived from a retrotransposon or an RNA retrovirus and confers on the fusion protein the ability to assemble into particles; an example is the product of the TYA gene of the yeast retrotransposon Ty. the second amino acid sequence is biologically active; for example it may be antigenic. So particles formed of the fusion proteins may be useful in vaccines or in diagnostic or purification applications.

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