Fusion proteins comprising a fragment of a chaperon polypeptide

Details Fusion proteins comprising a fragment of a chaperon polypeptide Fusion proteins comprising a fragment of a chaperon polypeptide

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 1/113 (2006.01) C07K 14/245 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 15/70 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2376062

The invention relates to a fusion protein comprising: a) a first region comprising a fragment of a chaperone polypeptide; and b) a second region not naturally associated with the first region comprising a polypeptide sequence of interest, as well as to nucleic acid sequences encoding such a fusion protein and methods for expressing polypeptides based on such nucleic acids.

L'invention concerne une protéine hybride qui comprend: a) une première région comprenant un fragment d'un polypeptide chaperon; et b) une seconde région qui n'est pas associée naturellement à la première région comprenant la séquence polypeptidique d'intérêt. L'invention concerne en outre des séquences d'acide nucléique codant cette protéine hybride et des méthodes d'expression de polypeptides basées sur lesdits acides nucléiques.

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