C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 39/00 (2006.01) C07K 7/23 (2006.01) C07K 14/03 (2006.01) C07K 16/26 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2297441
The subject invention provides a fusion protein for producing a dual immune response in a vertebrate, which fusion protein comprises: (a) a first proteinaceous portion analogous to all or part of a peptide endogenously synthesized within the vertebrate, the activity of which peptide is to be inhibited within the vertebrate, and which proteinaceous portion by itself is incapable of eliciting an effective immunoinhibitory response in said vertebrate; connected to (b) a second proteinaceous portion analogous to all or part of an immunogen from a pathogen, which pathogen is capable of pathogenically infecting the vertebrate; the portion (b) causing the vertebrate's immune system to recognize the portion (a) and produce a response that: (i) inhibits the activity of the peptide endogenously synthesized within the vertebrate; and (ii) protects the vertebrate from infection by the pathogen, when the vertebrate is vaccinated with an effective amount of the fusion protein. The subject invention also provides fusion proteins which comprise a proteinaceous portion (b) that is a carrier that is analogous to all or part of a BHV-1 antigen, which fusion proteins induce in a vertebrate vaccinated with an effective amount of such fusion protein an immune response that inhibits the activity of a peptide as recited in (a), above.
Campos Manuel
Durtschi Becky Ann
Martinod Serge Rene
Yule Terecita Dolores
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Pfizer Products Inc.
LandOfFree
Fusion proteins comprising carriers that can induce a dual... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fusion proteins comprising carriers that can induce a dual..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fusion proteins comprising carriers that can induce a dual... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1956371