Fusion proteins comprising cd4 minimal modules and methods...

Details Fusion proteins comprising cd4 minimal modules and methods... Fusion proteins comprising cd4 minimal modules and methods...

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01)

Patent

CA 2569562

Fusion proteins comprising CD4 minimal modules that bind to HIV Env polypeptides in a non-CD4 backbone are described. Also described are complexes of these fusion proteins with Env as well as methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided.

La présente invention concerne des protéines de fusion comprenant des modules CD4 minimaux se liant aux polypeptides Env du VIH dans une ossature non CD4. L'invention concerne également des complexes de ces protéines de fusion avec l'Env ainsi que des procédés permettant le diagnostic, le traitement et la prévention au moyen de ces polynucléotides et polypeptides.

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